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Can Biology Replace Mining? The Future of Critical Minerals

EUVC Live at GoWest

Introduced by Andreas Munk Holm, this EUVC Live at GoWest series spotlights the thought leadership of policymakers, institutional investors, GPs, corporates, and public capital leaders around one defining question:

How does Europe mobilize its own capital to secure its technological future?

Across the sessions, one theme emerges repeatedly:

Europe does not lack talent.
It does not lack innovation.
It does not lack savings.

It lacks coordination.


In this episode, Dr. Isabella Fandrych, Co-Founder and General Partner at Nucleus Capital, explores one of the energy transition’s most fragile bottlenecks:

Access to critical minerals.

Because decarbonization is not only about electricity.

It is about materials.

Lithium.
Copper.
Rare earths.

And today, extracting them is

  • Energy-intensive.

  • Chemically aggressive.

  • Environmentally destructive.

  • Geopolitically concentrated.

But what if the next mining superpower wasn’t a country?

What if it were a microbe?

Industrial biotechnology introduces a different extraction logic:

Not heat and blasting.
But biology and precision.

Microbes that leach metals from low-grade ores.
Proteins engineered to bind lithium from waste streams.
Plants designed to accumulate metals from soil.
Biological recovery from e-waste and industrial residues.

The reframe is powerful:

The problem is not only scarcity.

It is inefficiency.

Vast amounts of value are trapped in tailings, waste rock, and industrial byproducts.

Biology turns waste into yield.

For Europe, the implications are strategic:

Mineral sovereignty will not come only from new mines.

It may come from science.

From circular supply chains.
Decentralized extraction.
And industrial biotech scaled into infrastructure.

We cannot electrify the future with 19th-century mining logic.

And the next industrial revolution may be biological

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The Hidden Constraint of Decarbonisation

Modern green technologies — batteries, wind turbines, EV motors, grid infrastructure — depend on minerals extracted through processes that are:

  • Energy-intensive

  • Chemically aggressive

  • Environmentally destructive

  • Geopolitically concentrated

At the same time:

  • Ore grades are declining

  • Extraction costs are rising

  • Environmental regulation is tightening

  • Strategic dependencies are deepening

The mineral transition risks becoming the weak link in the energy transition.

Scaling renewables without reinventing extraction risks replacing one environmental burden with another.


Reprogramming Nature for Industry

Traditional mining relies on heat, pressure, blasting, and solvents.

Industrial biotechnology asks a different question:

What if we used biology instead of brute force?

Microorganisms, enzymes, and engineered plants can extract and recover metals with molecular precision.

Technologies covered include:

  • Microbial mining (bioleaching): Bacteria separating metals from low-grade ores

  • Protein engineering: Designing proteins that selectively bind lithium, copper, or rare earths from liquid waste streams

  • Phytomining: Engineering plants to accumulate metals like nickel directly from soil

  • Biological urban mining: Recovering critical minerals from e-waste and industrial residues

These systems operate:

  • At lower temperatures

  • With reduced chemical inputs

  • On materials previously considered uneconomical

Biology turns waste into yield.


From Scarcity to Yield Optimization

One of the keynote’s most important reframes:

The problem is not only scarcity.

It is inefficiency.

Vast quantities of valuable minerals are

  • Trapped in tailings and waste rock

  • Lost in industrial effluents

  • Dispersed across electronic waste

  • Embedded in soils at marginal concentrations

Biological systems excel at selective binding and molecular recognition.

By engineering microbes and proteins, researchers can dramatically increase recovery rates while reducing environmental footprint.

Mining becomes less about expansion.

More about optimization.


Sovereignty Through Science

For Europe, the implications are strategic.

Critical minerals such as lithium, cobalt, nickel, and rare earth elements are heavily concentrated in a handful of geographies.

Traditional mining expansion is:

  • Capital-intensive

  • Politically sensitive

  • Environmentally contested

  • Slow to scale

Industrial biotech offers an alternative:

  • Lower-barrier mineral recovery

  • Decentralised extraction models

  • Circular supply chains

  • Reduced reliance on geopolitically sensitive imports

Instead of chasing new mines abroad, Europe could extract value from:

Its waste.
Its industrial byproducts.
Its underutilised deposits.

Startups across Europe are already piloting these approaches.

The science exists.

The question is scale.


A Biological Industrial Revolution

The first industrial revolution was mechanical.

The second was electrical.

The third was digital.

The next may be biological.

Decarbonisation requires materials at unprecedented scale.

If extraction remains carbon-heavy and geopolitically concentrated, the transition remains fragile.

Dr. Fandrych’s core message is direct:

We cannot electrify the future with 19th-century mining logic.

By turning microbes, proteins, and plants into industrial tools, Europe can:

  • Increase mineral yield

  • Reduce chemical intensity

  • Strengthen supply chain resilience

  • Build sovereign capacity in critical materials

Decarbonization needs materials.

Biology may be the cleanest way to get them.


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