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Damian Cristian & Guy Conway, Rule 30: Building the First Fully Systematic VC

Rule 30’s founders explain why “access” at pre-seed is overrated, why follow-ons often destroy EV, and how an AI decision engine can consistently pick better distributions — not just better anecdotes.

Welcome back to the EUVC Podcast, your inside track on the people, models, and math reshaping European venture.

This week, Andreas talks with Damian Cristian and Guy Conway, co-founders of Rule 30 - an AI research lab building what they claim is the world’s first fully systematic venture strategy. We go deep on the difference between “data-driven” (hygiene) and decision-driven (engine), why labels matter, and how portfolio math crushes intuition.

They unpack founder-trajectory signals, graph-based network evolution, market topology (yes, biology-inspired stats), and a portfolio design targeting 3x+ minimum returns with 97.5% confidence. We also debate the “access myth,” party rounds, and why they won’t sell their alpha.

Whether you’re an LP testing managers, a GP rethinking reserves, or a founder curious how algorithms “see” you - this one’s for the nerds and the pragmatists.

Here’s what’s covered:

  • 01:46 | What is “Quant VC” and how it differs from traditional venture

  • 06:39 | Why pre-seed isn’t an access problem — it’s a triage problem

  • 09:55 | Can AI really make investment decisions at pre-seed?

  • 14:13 | Training the model on 15 years of startup data to find top-decile winners

  • 20:55 | The “Outlier Trajectory” of founders — decoding team evolution through data

  • 26:42 | Why Rule 30 calls itself an AI Research Lab, not a VC fund

  • 35:36 | Portfolio construction math: the danger of the “middle” strategy

  • 55:57 | Follow-ons vs upfront bets — why they avoid reserves entirely

  • 61:40 | Access myth-busting — why 99 % of pre-seed deals are open to smart capital

🎧 Listen on Apple or Spotify — chapters are set for easy navigation.


✍️ Show Notes

Quant vs Data-Driven (and why it matters)

  • “Data-driven” is hygiene (more signals, cleaner CRMs). Quant is a decision engine that actually picks based on learned patterns — and sticks to them even when the room culture disagrees.

  • Training set: yearly cohorts since 2010; outcome label = top decile in valuation delta from first round (portfolio-level DPI proxy), not “pick unicorns.”


Signals that Consistently Pop

  • Founder Outlier Trajectory: time-series of roles, network slope, and cohort-relative progression; compares “ideal team” vs actual team and measures delta against 20k+ labeled comps.

  • Graph evolution: pre-investment network dynamics that foreshadow which investors are likely to show up.

  • Market topology: abstract competitive spaces with stats inspired by quant finance & biology.

“People assume there isn’t enough data at pre-seed. The truth is there isn’t enough human-computable data. The algorithms can.” — Damian


Portfolio Construction (a quantified stance)

  • Two strategies work historically: very wide (index-like) or ultra-concentrated (true benchmark-style). The “30–40 deals + vibes + reserves” middle is a valley of death.

  • Rule 30 targets 75–85 initial checks, no reserves, and separate follow-on vehicles only for strategic reasons.

  • Goal: reduce volatility of the asset class; design for ≥3x with high confidence, not lottery-ticket 40x paired with 0.3x.

“If you can write the bigger check upfront, EV says do it. ‘Double-down later’ sounds great — it’s usually worse than sizing right at entry.” — Damian


Access at Pre-Seed (myth-busting)

  • Hypothesis borne out so far: access isn’t the bottleneck for ~99% of pre-seed rounds; the 1% you can’t access are usually mispriced anyway.

  • Technical founders like engaging an algorithmic IC; auto-memos increase trust and speed.

Why an AI Research Lab?

  • They won’t sell the alpha as SaaS. Mandate is to mine it — possibly with LP partnerships — and expand from pre-seed to later stages and adjacent private-market strategies.

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